FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific,...
FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity
About this item
Full title
Author / Creator
Fanciulli, Manuela , Norsworthy, Penny J , Petretto, Enrico , Dong, Rong , Harper, Lorraine , Kamesh, Lavanya , Heward, Joanne M , Gough, Stephen C L , de Smith, Adam , Blakemore, Alexandra I F , Froguel, Philippe , Owen, Catherine J , Pearce, Simon H S , Teixeira, Luis , Guillevin, Loic , Graham, Deborah S Cunninghame , Pusey, Charles D , Cook, H Terence , Vyse, Timothy J and Aitman, Timothy J
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Naturally occurring variation in gene copy number is increasingly recognized as a heritable source of susceptibility to genetically complex diseases. Here we report strong association between
FCGR3B
copy number and risk of systemic lupus erythematosus (
P
= 2.7 × 10
−8
), microscopic polyangiitis (
P
= 2.9 × 10
−4
) an...
Alternative Titles
Full title
FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity
Authors, Artists and Contributors
Author / Creator
Norsworthy, Penny J
Petretto, Enrico
Dong, Rong
Harper, Lorraine
Kamesh, Lavanya
Heward, Joanne M
Gough, Stephen C L
de Smith, Adam
Blakemore, Alexandra I F
Froguel, Philippe
Owen, Catherine J
Pearce, Simon H S
Teixeira, Luis
Guillevin, Loic
Graham, Deborah S Cunninghame
Pusey, Charles D
Cook, H Terence
Vyse, Timothy J
Aitman, Timothy J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2742197
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2742197
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng2046
