Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
About this item
Full title
Author / Creator
Michalak, E M , Jansen, E S , Happo, L , Cragg, M S , Tai, L , Smyth, G K , Strasser, A , Adams, J M and Scott, C L
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
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Scope and Contents
Contents
Evasion of apoptosis contributes importantly to c-Myc-induced tumorigenesis. The BH3-only Bcl-2 family members Puma and Noxa are critical pro-apoptotic transcriptional targets of p53, a major mediator of Myc-induced apoptosis and suppressor of Myc-induced tumorigenesis. Hence, we have explored the impact of their individual or combined loss on
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Alternative Titles
Full title
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2743939
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2743939
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2008.195
