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SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes a...

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2752084

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

About this item

Full title

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2009-10, Vol.119 (10), p.2914-2924

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Various acute and chronic inflammatory stimuli increase the number and activity of pulmonary mucus-producing goblet cells, and goblet cell hyperplasia and excess mucus production are central to the pathogenesis of chronic pulmonary diseases. However, little is known about the transcriptional programs that regulate goblet cell differentiation. Here,...

Alternative Titles

Full title

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2752084

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2752084

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI39731

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