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Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2768268

Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

About this item

Full title

Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2006-11, Vol.12 (11), p.1286-1293

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The angiogenic growth factor angiopoietin 2 (Ang2) destabilizes blood vessels, enhances vascular leak and induces vascular regression and endothelial cell apoptosis. We considered that Ang2 might be important in hyperoxic acute lung injury (ALI). Here we have characterized the responses in lungs induced by hyperoxia in wild-type and
Ang2
−/−<...

Alternative Titles

Full title

Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2768268

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2768268

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1494

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