Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
About this item
Full title
Author / Creator
Ban, Maria , Goris, An , Lorentzen, Åslaug R , Baker, Amie , Mihalova, Tania , Ingram, Gillian , Booth, David R , Heard, Robert N , Stewart, Graeme J , Bogaert, Elke , Dubois, Bénédicte , Harbo, Hanne F , Celius, Elisabeth G , Spurkland, Anne , Strange, Richard , Hawkins, Clive , Robertson, Neil P , Dudbridge, Frank , Wason, James , De Jager, Philip L , Hafler, David , Rioux, John D , Ivinson, Adrian J , McCauley, Jacob L , Pericak-Vance, Margaret , Oksenberg, Jorge R , Hauser, Stephen L , Sexton, David , Haines, Jonathan , Sawcer, Stephen , The Wellcome Trust Case–Control Consortium (WTCCC) and Alastair Compston and Wellcome Trust Case-Control Consortium (WTCCC)
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
In a recent genome-wide association study (GWAS) based on 12 374 non-synonymous single nucleotide polymorphisms we identified a number of candidate multiple sclerosis susceptibility genes. Here, we describe the extended analysis of 17 of these loci undertaken using an additional 4234 patients, 2983 controls and 2053 trio families. In the final anal...
Alternative Titles
Full title
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
Authors, Artists and Contributors
Author / Creator
Goris, An
Lorentzen, Åslaug R
Baker, Amie
Mihalova, Tania
Ingram, Gillian
Booth, David R
Heard, Robert N
Stewart, Graeme J
Bogaert, Elke
Dubois, Bénédicte
Harbo, Hanne F
Celius, Elisabeth G
Spurkland, Anne
Strange, Richard
Hawkins, Clive
Robertson, Neil P
Dudbridge, Frank
Wason, James
De Jager, Philip L
Hafler, David
Rioux, John D
Ivinson, Adrian J
McCauley, Jacob L
Pericak-Vance, Margaret
Oksenberg, Jorge R
Hauser, Stephen L
Sexton, David
Haines, Jonathan
Sawcer, Stephen
The Wellcome Trust Case–Control Consortium (WTCCC) and Alastair Compston
Wellcome Trust Case-Control Consortium (WTCCC)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2782567
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2782567
Other Identifiers
ISSN
1018-4813
E-ISSN
1476-5438
DOI
10.1038/ejhg.2009.41
