A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The SARS coronavirus protein nsp1 can suppress host gene expression at a post-transcriptional level, with previous work showing a reduction in mRNA abundance. Now a direct effect on protein synthesis is revealed, as nsp1 modifies transcripts and also inactivates the 40S ribosomal subunit.
Severe acute respiratory syndrome coronavirus nsp1 protei...
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Full title
A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2784181
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2784181
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.1680
