Defective Survival of Naive CD8+ T Lymphocytes in the absence of β3 regulatory subunit of Cav channe...
Defective Survival of Naive CD8+ T Lymphocytes in the absence of β3 regulatory subunit of Cav channels
About this item
Full title
Defective Survival of Naive CD8+ T Lymphocytes in the absence of β3 regulatory subunit of Cav channels
Author / Creator
Journal title
Nature immunology, 2009-10, Vol.10 (12), p.1275-1282
Language
English
Formats
More information
Scope and Contents
Contents
Survival of T lymphocytes requires sustained Ca
2+
influx-dependent gene expression. The molecular mechanism, which governs sustained Ca
2+
influx in naive T lymphocytes, is unknown. Here we report an essential role for the β3 regulatory subunit of Ca
v
channels in the maintenance of naive CD8
+
T cells. β3 deficiency result...
Alternative Titles
Full title
Defective Survival of Naive CD8+ T Lymphocytes in the absence of β3 regulatory subunit of Cav channels
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2785134
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2785134
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1793
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