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Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786791

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

About this item

Full title

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2009-12, Vol.119 (12), p.3613-3625

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Membrane-bound proteases have recently emerged as critical mediators of tumorigenesis, angiogenesis, and metastasis. However, the mechanisms by which they regulate these processes remain unknown. As the cell surface serine protease fibroblast activation protein (FAP) is selectively expressed on tumor-associated fibroblasts and pericytes in epitheli...

Alternative Titles

Full title

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786791

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786791

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI38988

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