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Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786798

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

About this item

Full title

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2009-12, Vol.119 (12), p.3723-3738

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The respiratory tract is continuously exposed to both innocuous airborne antigens and immunostimulatory molecules of microbial origin, such as LPS. At low concentrations, airborne LPS can induce a lung DC-driven Th2 cell response to harmless inhaled antigens, thereby promoting allergic asthma. However, only a small fraction of people exposed to env...

Alternative Titles

Full title

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786798

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786798

Other Identifiers

ISSN

0021-9738,1558-8238

E-ISSN

1558-8238

DOI

10.1172/JCI39717

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