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Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I...

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786805

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

About this item

Full title

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2009-12, Vol.119 (12), p.3544-3555

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

African green monkeys (AGMs) infected with the AGM type of SIV (SIVagm) do not develop chronic immune activation and AIDS, despite viral loads similar to those detected in humans infected with HIV-1 and rhesus macaques (RMs) infected with the RM type of SIV (SIVmac). Because chronic immune activation drives progressive CD4+ T cell depletion and imm...

Alternative Titles

Full title

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786805

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786805

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI40093

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