Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I...
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response
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Author / Creator
Jacquelin, Béatrice , Mayau, Véronique , Targat, Brice , Liovat, Anne-Sophie , Kunkel, Désirée , Petitjean, Gaël , Dillies, Marie-Agnès , Roques, Pierre , Butor, Cécile , Silvestri, Guido , Giavedoni, Luis D. , Lebon, Pierre , Barré-Sinoussi, Françoise , Benecke, Arndt and Müller-Trutwin, Michaela C.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
African green monkeys (AGMs) infected with the AGM type of SIV (SIVagm) do not develop chronic immune activation and AIDS, despite viral loads similar to those detected in humans infected with HIV-1 and rhesus macaques (RMs) infected with the RM type of SIV (SIVmac). Because chronic immune activation drives progressive CD4+ T cell depletion and imm...
Alternative Titles
Full title
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786805
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2786805
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI40093