Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Frank Costantini and colleagues report the identification of the ETS transcription factors, Etv4 and Etv5, as key targets of Ret signaling during kidney branching morphogenesis. Loss of Etv4 and Etv5 function in mice leads to complete failure of kidney development.
Glial cell line–derived neurotrophic factor signaling through the Ret receptor ty...
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Full title
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2787691
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2787691
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.476
