Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snai...
Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Nicholas Hastie and colleagues show that Wt1 is required for the epithelial-to-mesenchymal (EMT) transition in the developing epicardium and the formation of mesenchymal cardiovascular progenitors. Wt1 directly regulates the transcription of Snail and E-cadherin, two well-known mediators of EMT.
The epicardial epithelial-mesenchymal transition (...
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Full title
Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2799392
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2799392
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.494
