Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide assoc...
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
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Author / Creator
Dehghan, Abbas, MD , Köttgen, Anna, MD , Yang, Qiong, PhD , Hwang, Shih-Jen, PhD , Kao, WH Linda, PhD , Rivadeneira, Fernando, MD , Boerwinkle, Eric, PhD , Levy, Daniel, MD , Hofman, Albert, MD , Astor, Brad C, PhD , Benjamin, Emelia J, MD , van Duijn, Cornelia M, PhD , Witteman, Jacqueline C, PhD , Coresh, Josef, MD and Fox, Caroline S, Dr
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes associated with serum uric acid concentration and gout. Methods Genome-wide association studies were done for serum uric acid in 7699 participants in the Framingham cohort and in 4148 participants in the Rotterdam cohort. Gen...
Alternative Titles
Full title
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
Authors, Artists and Contributors
Author / Creator
Köttgen, Anna, MD
Yang, Qiong, PhD
Hwang, Shih-Jen, PhD
Kao, WH Linda, PhD
Rivadeneira, Fernando, MD
Boerwinkle, Eric, PhD
Levy, Daniel, MD
Hofman, Albert, MD
Astor, Brad C, PhD
Benjamin, Emelia J, MD
van Duijn, Cornelia M, PhD
Witteman, Jacqueline C, PhD
Coresh, Josef, MD
Fox, Caroline S, Dr
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Primary Identifiers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2803340
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2803340
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(08)61343-4