Increased Matrix Metalloproteinase 9 Activity in Mild Cognitive Impairment
Increased Matrix Metalloproteinase 9 Activity in Mild Cognitive Impairment
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Author / Creator
Publisher
Hagerstown, MD: American Association of Neuropathologists, Inc
Journal title
Language
English
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Publication information
Publisher
Hagerstown, MD: American Association of Neuropathologists, Inc
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Scope and Contents
Contents
Nerve growth factor (NGF)-dependent cholinergic basal forebrain neurons degenerate during the progression of Alzheimer disease (AD). Elevated proNGF and reduced levels of the TrkA high-affinity NGF receptor occur in prodromal and advanced stages of AD. We recently described a protease cascade responsible for the conversion of proNGF to mature NGF (...
Alternative Titles
Full title
Increased Matrix Metalloproteinase 9 Activity in Mild Cognitive Impairment
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2810197
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2810197
Other Identifiers
ISSN
0022-3069
E-ISSN
1554-6578
DOI
10.1097/NEN.0b013e3181c22569
