Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, he...
Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients
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Author / Creator
Zlobec, I , Molinari, F , Kovac, M , Bihl, M P , Altermatt, H J , Diebold, J , Frick, H , Germer, M , Horcic, M , Montani, M , Singer, G , Yurtsever, H , Zettl, A , Terracciano, L , Mazzucchelli, L , Saletti, P , Frattini, M , Heinimann, K and Lugli, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background:
Our aim was to investigate the prognostic and predictive value of the oncogenic MAPKK-like protein T-cell-originated protein kinase (TOPK) stratified by
KRAS
and
BRAF
mutations in patients with sporadic, hereditary and metastatic colorectal cancer (CRC) treated with anti-EGFR therapy.
Methods:
Immunohistochemistry (...
Alternative Titles
Full title
Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2813744
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2813744
Other Identifiers
ISSN
0007-0920,1532-1827
E-ISSN
1532-1827
DOI
10.1038/sj.bjc.6605452