A Dual-Fluorescence High-Throughput Cell Line System for Probing Multidrug Resistance
A Dual-Fluorescence High-Throughput Cell Line System for Probing Multidrug Resistance
About this item
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Author / Creator
Publisher
United States: Mary Ann Liebert, Inc
Journal title
Language
English
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Publication information
Publisher
United States: Mary Ann Liebert, Inc
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Scope and Contents
Contents
The efflux pump P-glycoprotein (ATP-binding cassette B1, multidrug resistance [MDR] 1, P-gp) has long been known to contribute to MDR against cancer chemotherapeutics. We describe the development of a dual-fluorescent cell line system to allow multiplexing of drug-sensitive and P-gp-mediated MDR cell lines. The parental OVCAR-8 human ovarian carcin...
Alternative Titles
Full title
A Dual-Fluorescence High-Throughput Cell Line System for Probing Multidrug Resistance
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2814070
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2814070
Other Identifiers
ISSN
1540-658X
E-ISSN
1557-8127
DOI
10.1089/adt.2008.165
