Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2
Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2
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Publisher
United States: American Thoracic Society
Journal title
Language
English
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Publisher
United States: American Thoracic Society
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Scope and Contents
Contents
The critical innate immune mechanisms that regulate granulomatous inflammation in sarcoidosis are unknown. Because the granuloma-inducing component of sarcoidosis tissues has physicochemical properties similar to those of amyloid fibrils, we hypothesized that host proteins capable of forming poorly soluble aggregates or amyloid regulate inflammatio...
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Full title
Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2822973
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2822973
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.200905-0696OC