Arylhydrocarbon Receptor Activation in NCI-H441 Cells and C57BL/6 Mice: Possible Mechanisms for Lung...
Arylhydrocarbon Receptor Activation in NCI-H441 Cells and C57BL/6 Mice: Possible Mechanisms for Lung Dysfunction
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Publisher
United States: Am Thoracic Soc
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Language
English
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United States: Am Thoracic Soc
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Contents
The arylhydrocarbon receptor (AhR) is known for its ability to bind aromatic-containing compounds, which starts a molecular cascade involving the induction of cytochrome P450s and inflammatory cytokines. Our hypothesis is that many inhaled environmental toxicant components activate these inflammatory pathways via an initial binding to the AhR. To t...
Alternative Titles
Full title
Arylhydrocarbon Receptor Activation in NCI-H441 Cells and C57BL/6 Mice: Possible Mechanisms for Lung Dysfunction
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2822982
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2822982
Other Identifiers
ISSN
1044-1549,1535-4989
E-ISSN
1535-4989
DOI
10.1165/rcmb.2008-0228OC
