Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones
Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones
About this item
Full title
Author / Creator
Maes, Christa , Goossens, Steven , Bartunkova, Sonia , Drogat, Benjamin , Coenegrachts, Lieve , Stockmans, Ingrid , Moermans, Karen , Nyabi, Omar , Haigh, Katharina , Naessens, Michael , Haenebalcke, Lieven , Tuckermann, Jan P , Tjwa, Marc , Carmeliet, Peter , Mandic, Vice , David, Jean-Pierre , Behrens, Axel , Nagy, Andras , Carmeliet, Geert and Haigh, Jody J
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
Vascular endothelial growth factor (VEGF) and β‐catenin both act broadly in embryogenesis and adulthood, including in the skeletal and vascular systems. Increased or deregulated activity of these molecules has been linked to cancer and bone‐related pathologies. By using novel mouse models to locally increase VEGF levels in the skeleton, we found th...
Alternative Titles
Full title
Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones
Authors, Artists and Contributors
Author / Creator
Goossens, Steven
Bartunkova, Sonia
Drogat, Benjamin
Coenegrachts, Lieve
Stockmans, Ingrid
Moermans, Karen
Nyabi, Omar
Haigh, Katharina
Naessens, Michael
Haenebalcke, Lieven
Tuckermann, Jan P
Tjwa, Marc
Carmeliet, Peter
Mandic, Vice
David, Jean-Pierre
Behrens, Axel
Nagy, Andras
Carmeliet, Geert
Haigh, Jody J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2824461
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2824461
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2009.361
