Hyperglycemia Impairs Proteasome Function by Methylglyoxal
Hyperglycemia Impairs Proteasome Function by Methylglyoxal
About this item
Full title
Author / Creator
Publisher
Alexandria, VA: American Diabetes Association
Journal title
Language
English
Formats
Publication information
Publisher
Alexandria, VA: American Diabetes Association
Subjects
More information
Scope and Contents
Contents
The ubiquitin-proteasome system is the main degradation machinery for intracellularly altered proteins. Hyperglycemia has been shown to increase intracellular levels of the reactive dicarbonyl methylglyoxal (MGO) in cells damaged by diabetes, resulting in modification of proteins and alterations of their function. In this study, the influence of MG...
Alternative Titles
Full title
Hyperglycemia Impairs Proteasome Function by Methylglyoxal
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2828656
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2828656
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db08-1565
