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Direct conversion of fibroblasts to functional neurons by defined factors

Direct conversion of fibroblasts to functional neurons by defined factors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2829121

Direct conversion of fibroblasts to functional neurons by defined factors

About this item

Full title

Direct conversion of fibroblasts to functional neurons by defined factors

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2010-02, Vol.463 (7284), p.1035-1041

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cellular differentiation and lineage commitment are considered to be robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. This raised the question of whether transcription factors could directly induce...

Alternative Titles

Full title

Direct conversion of fibroblasts to functional neurons by defined factors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2829121

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2829121

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature08797

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