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Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2831214

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

About this item

Full title

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2010-03, Vol.6 (3), p.209-217

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Cycloheximide is a natural product that cell biologists have used for decades as a tool to arrest protein synthesis in eukaryotes. Biochemical data now refine our mechanistic view of how cycloheximide and structurally related analogs inhibit translational elongation.
Although the protein synthesis inhibitor cycloheximide (CHX) has been known for...

Alternative Titles

Full title

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2831214

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2831214

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.304

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