Reversible Inhibitors of Monoamine Oxidase-A (RIMAs): Robust, Reversible Inhibition of Human Brain M...
Reversible Inhibitors of Monoamine Oxidase-A (RIMAs): Robust, Reversible Inhibition of Human Brain MAO-A by CX157
About this item
Full title
Author / Creator
Fowler, Joanna S , Logan, Jean , Azzaro, Albert J , Fielding, Robert M , Zhu, Wei , Poshusta, Amy K , Burch, Daniel , Brand, Barry , Free, James , Asgharnejad, Mahnaz , Wang, Gene-Jack , Telang, Frank , Hubbard, Barbara , Jayne, Millard , King, Payton , Carter, Pauline , Carter, Scott , Xu, Youwen , Shea, Colleen , Muench, Lisa , Alexoff, David , Shumay, Elena , Schueller, Michael , Warner, Donald and Apelskog-Torres, Karen
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
Reversible inhibitors of monoamine oxidase-A (RIMA) inhibit the breakdown of three major neurotransmitters, serotonin, norepinephrine and dopamine, offering a multi-neurotransmitter strategy for the treatment of depression. CX157 (3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin-10,10-dioxide) is a RIMA, which is currently in development for the trea...
Alternative Titles
Full title
Reversible Inhibitors of Monoamine Oxidase-A (RIMAs): Robust, Reversible Inhibition of Human Brain MAO-A by CX157
Authors, Artists and Contributors
Author / Creator
Logan, Jean
Azzaro, Albert J
Fielding, Robert M
Zhu, Wei
Poshusta, Amy K
Burch, Daniel
Brand, Barry
Free, James
Asgharnejad, Mahnaz
Wang, Gene-Jack
Telang, Frank
Hubbard, Barbara
Jayne, Millard
King, Payton
Carter, Pauline
Carter, Scott
Xu, Youwen
Shea, Colleen
Muench, Lisa
Alexoff, David
Shumay, Elena
Schueller, Michael
Warner, Donald
Apelskog-Torres, Karen
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2833271
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2833271
Other Identifiers
ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/npp.2009.167