HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Scope and Contents
Contents
Autophagy is primarily considered a non‐selective degradation process induced by starvation. Nutrient‐independent basal autophagy, in contrast, imposes intracellular QC by selective disposal of aberrant protein aggregates and damaged organelles, a process critical for suppressing neurodegenerative diseases. The molecular mechanism that distinguishe...
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Full title
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2837169
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2837169
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2009.405