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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2837169

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

About this item

Full title

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2010-03, Vol.29 (5), p.969-980

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Autophagy is primarily considered a non‐selective degradation process induced by starvation. Nutrient‐independent basal autophagy, in contrast, imposes intracellular QC by selective disposal of aberrant protein aggregates and damaged organelles, a process critical for suppressing neurodegenerative diseases. The molecular mechanism that distinguishe...

Alternative Titles

Full title

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2837169

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2837169

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2009.405

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