Evidence of STAT5‐dependent and ‐independent routes to CD8 memory formation and a preferential role...
Evidence of STAT5‐dependent and ‐independent routes to CD8 memory formation and a preferential role for IL‐7 over IL‐15 in STAT5 activation
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United States: Nature Publishing Group
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English
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United States: Nature Publishing Group
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Interleukin (IL)‐7 and IL‐15 have non‐redundant roles in promoting development of memory CD8+ T cells. STAT5 is activated by receptors of both cytokines and has also been implicated as a requirement for generation of memory. To determine whether STAT5 activity was required for IL‐7 and IL‐15‐mediated generation of memory, we expressed either wild t...
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Full title
Evidence of STAT5‐dependent and ‐independent routes to CD8 memory formation and a preferential role for IL‐7 over IL‐15 in STAT5 activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2842934
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2842934
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ISSN
0818-9641
E-ISSN
1440-1711
DOI
10.1038/icb.2009.95