The Ashwell receptor mitigates the lethal coagulopathy of sepsis
The Ashwell receptor mitigates the lethal coagulopathy of sepsis
About this item
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The Ashwell receptor, the major lectin of hepatocytes, rapidly clears from blood circulation glycoproteins bearing glycan ligands that include galactose and
N
-acetylgalactosamine. This asialoglycoprotein receptor activity remains a key factor in the development and administration of glycoprotein pharmaceuticals, yet a biological purpose of t...
Alternative Titles
Full title
The Ashwell receptor mitigates the lethal coagulopathy of sepsis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2853759
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2853759
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1760
