Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Human RNAi therapy
The ability to downregulate specific genes using systemically delivered short RNA molecules and the cellular mechanism known as RNA interference has been shown previously in mouse and non-human primate models. Davis
et al
. have now demonstrated for the first time in humans that a short interfering RNA (siRNA) molecule c...
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Full title
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2855406
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2855406
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08956
