Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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T helper cells: IRF4 in control
The X-chromosome-encoded transcription factor Foxp3 is thought to play a key role in the immune response as a regulator of the differentiation and suppressor function of regulatory T cells (T
reg
cells). Zheng
et al
. show here that regulatory T cells express the transcription factor IRF4 (interferon r...
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Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2864791
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2864791
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature07674
