Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy
Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy
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Author / Creator
Publisher
Waltham, MA: Massachusetts Medical Society
Journal title
Language
English
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Publisher
Waltham, MA: Massachusetts Medical Society
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Scope and Contents
Contents
This study examined bone-biopsy specimens obtained after a 3-year, double-blind, randomized, placebo-controlled, dose-ranging trial of oral alendronate to prevent bone resorption in healthy postmenopausal women. Long-term alendronate treatment was associated with an increase in the number of osteoclasts, which include distinctive giant, hypernuclea...
Alternative Titles
Full title
Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866022
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866022
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0802633