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Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy

Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866022

Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy

About this item

Full title

Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy

Publisher

Waltham, MA: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2009-01, Vol.360 (1), p.53-62

Language

English

Formats

Publication information

Publisher

Waltham, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

This study examined bone-biopsy specimens obtained after a 3-year, double-blind, randomized, placebo-controlled, dose-ranging trial of oral alendronate to prevent bone resorption in healthy postmenopausal women. Long-term alendronate treatment was associated with an increase in the number of osteoclasts, which include distinctive giant, hypernuclea...

Alternative Titles

Full title

Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866022

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866022

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa0802633

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