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Negative regulation of the deacetylase SIRT1 by DBC1

Negative regulation of the deacetylase SIRT1 by DBC1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866287

Negative regulation of the deacetylase SIRT1 by DBC1

About this item

Full title

Negative regulation of the deacetylase SIRT1 by DBC1

Publisher

London: Nature Publishing Group UK

Journal title

Nature, 2008-01, Vol.451 (7178), p.587-590

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Linking ageing and cancer
The deacetylase SIRT1, the mammalian version of the Sir2 protein that plays a critical role in determining lifespan in yeast, has been implicated in various cellular functions and possibly in tumorigenesis and ageing. The factors regulating SIRT1 are not well known but two groups now report that the tumour suppressor DB...

Alternative Titles

Full title

Negative regulation of the deacetylase SIRT1 by DBC1

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866287

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866287

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687,1476-4679

DOI

10.1038/nature06515

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