Negative regulation of the deacetylase SIRT1 by DBC1
Negative regulation of the deacetylase SIRT1 by DBC1
About this item
Full title
Author / Creator
Zhao, Wenhui , Kruse, Jan-Philipp , Tang, Yi , Jung, Sung Yun , Qin, Jun and Gu, Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Linking ageing and cancer
The deacetylase SIRT1, the mammalian version of the Sir2 protein that plays a critical role in determining lifespan in yeast, has been implicated in various cellular functions and possibly in tumorigenesis and ageing. The factors regulating SIRT1 are not well known but two groups now report that the tumour suppressor DB...
Alternative Titles
Full title
Negative regulation of the deacetylase SIRT1 by DBC1
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866287
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2866287
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature06515