Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
About this item
Full title
Author / Creator
Han, Qian , Cai, Tao , Tagle, Danilo A and Li, Jianyong
Publisher
Basel: Basel : SP Birkhäuser Verlag Basel
Journal title
Language
English
Formats
Publication information
Publisher
Basel: Basel : SP Birkhäuser Verlag Basel
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More information
Scope and Contents
Contents
Kynurenine aminotransferases (KATs) catalyze the synthesis of kynurenic acid (KYNA), an endogenous antagonist of N-methyl-d-aspartate and alpha 7-nicotinic acetylcholine receptors. Abnormal KYNA levels in human brains are implicated in the pathophysiology of schizophrenia, Alzheimer's disease, and other neurological disorders. Four KATs have been r...
Alternative Titles
Full title
Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2867614
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2867614
Other Identifiers
ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-009-0166-4
