Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-speci...
Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2
About this item
Full title
Author / Creator
Grigorieva, Irina V. , Mirczuk, Samantha , Gaynor, Katherine U. , Nesbit, M. Andrew , Grigorieva, Elena F. , Wei, Qiaozhi , Ali, Asif , Fairclough, Rebecca J. , Stacey, Joanna M. , Stechman, Michael J. , Mihai, Radu , Kurek, Dorota , Fraser, William D. , Hough, Tertius , Condie, Brian G. , Manley, Nancy , Grosveld, Frank and Thakker, Rajesh V.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Heterozygous mutations of GATA3, which encodes a dual zinc-finger transcription factor, cause hypoparathyroidism with sensorineural deafness and renal dysplasia. Here, we have investigated the role of GATA3 in parathyroid function by challenging Gata3+/- mice with a diet low in calcium and vitamin D so as to expose any defects in parathyroid functi...
Alternative Titles
Full title
Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2
Authors, Artists and Contributors
Author / Creator
Mirczuk, Samantha
Gaynor, Katherine U.
Nesbit, M. Andrew
Grigorieva, Elena F.
Wei, Qiaozhi
Ali, Asif
Fairclough, Rebecca J.
Stacey, Joanna M.
Stechman, Michael J.
Mihai, Radu
Kurek, Dorota
Fraser, William D.
Hough, Tertius
Condie, Brian G.
Manley, Nancy
Grosveld, Frank
Thakker, Rajesh V.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2877956
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2877956
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI42021
