Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation
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Author / Creator
Rudolph, Volker , Andrié, René P , Rudolph, Tanja K , Friedrichs, Kai , Klinke, Anna , Hirsch-Hoffmann, Birgit , Schwoerer, Alexander P , Lau, Denise , Fu, XiaoMing , Klingel, Karin , Sydow, Karsten , Didié, Michael , Seniuk, Anika , von Leitner, Eike-Christin , Szoecs, Katalin , Schrickel, Jan W , Treede, Hendrik , Wenzel, Ulrich , Lewalter, Thorsten , Nickenig, Georg , Zimmermann, Wolfram-Hubertus , Meinertz, Thomas , Böger, Rainer H , Reichenspurner, Hermann , Freeman, Bruce A , Eschenhagen, Thomas , Ehmke, Heimo , Hazen, Stanley L , Willems, Stephan and Baldus, Stephan
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Although the precipitating mechanisms of atrial fibrillation are not fully understood, atrial fibrosis is thought to set the stage for arrhythmia. Volker Rudolph
et al
. now show that the enzyme myeloperoxidase, released by inflammatory cells, is a key inducer of atrial fibrosis and arrhythmia in a mouse model of atrial fibrillation, and that...
Alternative Titles
Full title
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation
Authors, Artists and Contributors
Author / Creator
Andrié, René P
Rudolph, Tanja K
Friedrichs, Kai
Klinke, Anna
Hirsch-Hoffmann, Birgit
Schwoerer, Alexander P
Lau, Denise
Fu, XiaoMing
Klingel, Karin
Sydow, Karsten
Didié, Michael
Seniuk, Anika
von Leitner, Eike-Christin
Szoecs, Katalin
Schrickel, Jan W
Treede, Hendrik
Wenzel, Ulrich
Lewalter, Thorsten
Nickenig, Georg
Zimmermann, Wolfram-Hubertus
Meinertz, Thomas
Böger, Rainer H
Reichenspurner, Hermann
Freeman, Bruce A
Eschenhagen, Thomas
Ehmke, Heimo
Hazen, Stanley L
Willems, Stephan
Baldus, Stephan
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2880896
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2880896
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2124