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HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2887091

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

About this item

Full title

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2009-12, Vol.41 (12), p.1290-1294

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Mary Carrington and colleagues follow up on an earlier association of a variant upstream of
HLA-C
to HIV viral load setpoint, showing that this variant is associated with high HLA-C cell surface expression and demonstrating a protective effect of the variant in viral load and disease progression.
A variant 35 kb upstream of the
HLA-C

Alternative Titles

Full title

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2887091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2887091

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/ng.486

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