Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed...
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Benzodiazepines and alpha2 adrenoceptor agonists exert opposing effects on innate immunity and mortality in animal models of infection. We hypothesized that sedation with dexmedetomidine (an alpha2 adrenoceptor agonist), as compared with lorazepam (a benzodiazepine), would provide greater improvements in clinical outcomes among septic patients than...
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Full title
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2887145
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2887145
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ISSN
1364-8535
E-ISSN
1466-609X,1364-8535
DOI
10.1186/cc8916
