p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis
p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis
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Author / Creator
Kirsch, David G , Santiago, Philip M , di Tomaso, Emmanuelle , Sullivan, Julie M , Hou, Wu-Shiun , Dayton, Talya , Jeffords, Laura B , Sodha, Pooja , Mercer, Kim L , Cohen, Rhianna , Takeuchi, Osamu , Korsmeyer, Stanley J , Bronson, Roderick T , Kim, Carla F , Haigis, Kevin M , Jain, Rakesh K and Jacks, Tyler
Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Acute exposure to ionizing radiation can cause lethal damage to the gastrointestinal (GI) tract, a condition called the GI syndrome. Whether the target cells affected by radiation to cause the GI syndrome are derived from the epithelium or endothelium and whether the target cells die by apoptosis or other mechanisms are controversial issues. Studyi...
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Full title
p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2897160
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2897160
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1166202