Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Ded...
Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Dedifferentiation in Monolayer
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Boston: Birkhäuser-Verlag
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Language
English
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Boston: Birkhäuser-Verlag
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Contents
Chondrocytes in articular cartilage normally exhibit high expression of collagen II and aggrecan but rapidly dedifferentiate to a fibroblastic phenotype if passaged in culture. Previous studies have suggested that the loss of chondrocyte phenotype is associated with changes in the structure of the F-actin cytoskeleton, which also controls cell mech...
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Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Dedifferentiation in Monolayer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898162
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898162
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ISSN
1865-5025
E-ISSN
1865-5033
DOI
10.1007/s12195-009-0077-3