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Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Ded...

Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Ded...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898162

Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Dedifferentiation in Monolayer

About this item

Full title

Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Dedifferentiation in Monolayer

Publisher

Boston: Birkhäuser-Verlag

Journal title

Cellular and molecular bioengineering, 2009-09, Vol.2 (3), p.395-404

Language

English

Formats

Publication information

Publisher

Boston: Birkhäuser-Verlag

More information

Scope and Contents

Contents

Chondrocytes in articular cartilage normally exhibit high expression of collagen II and aggrecan but rapidly dedifferentiate to a fibroblastic phenotype if passaged in culture. Previous studies have suggested that the loss of chondrocyte phenotype is associated with changes in the structure of the F-actin cytoskeleton, which also controls cell mech...

Alternative Titles

Full title

Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Dedifferentiation in Monolayer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898162

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898162

Other Identifiers

ISSN

1865-5025

E-ISSN

1865-5033

DOI

10.1007/s12195-009-0077-3

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