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Chromatin regulation by Brg1 underlies heart muscle development and disease

Chromatin regulation by Brg1 underlies heart muscle development and disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898892

Chromatin regulation by Brg1 underlies heart muscle development and disease

About this item

Full title

Chromatin regulation by Brg1 underlies heart muscle development and disease

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2010-07, Vol.466 (7302), p.62-67

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cardiac hypertrophy and failure are characterized by transcriptional reprogramming of gene expression. Adult cardiomyocytes in mice primarily express α-myosin heavy chain (
α-MHC
, also known as
Myh6
), whereas embryonic cardiomyocytes express
β-MHC
(also known as
Myh7
). Cardiac stress triggers adult hearts to undergo hyper...

Alternative Titles

Full title

Chromatin regulation by Brg1 underlies heart muscle development and disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898892

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2898892

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature09130

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