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Cancer-selective apoptotic effects of extracellular and intracellular Par-4

Cancer-selective apoptotic effects of extracellular and intracellular Par-4

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2900490

Cancer-selective apoptotic effects of extracellular and intracellular Par-4

About this item

Full title

Cancer-selective apoptotic effects of extracellular and intracellular Par-4

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2010-07, Vol.29 (27), p.3873-3880

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Selectivity toward cancer cells is the most desirable element in cancer therapeutics. Par-4 is a cancer cell-selective proapoptotic protein that functions intracellularly in the cytoplasmic and nuclear compartments as a tumor suppressor. Moreover, recent findings indicate that the Par-4 protein is secreted by cells, and extracellular Par-4 induces...

Alternative Titles

Full title

Cancer-selective apoptotic effects of extracellular and intracellular Par-4

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2900490

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2900490

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2010.141

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