IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
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Author / Creator
Aujla, Shean J , Chan, Yvonne R , Zheng, Mingquan , Fei, Mingjian , Askew, David J , Pociask, Derek A , Reinhart, Todd A , McAllister, Florencia , Edeal, Jennifer , Gaus, Kristi , Husain, Shahid , Kreindler, James L , Dubin, Patricia J , Pilewski, Joseph M , Myerburg, Mike M , Mason, Carol A , Iwakura, Yoichiro and Kolls, Jay K
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Emerging evidence supports the concept that T helper type 17 (T
H
17) cells, in addition to mediating autoimmunity, have key roles in mucosal immunity against extracellular pathogens. Interleukin-22 (IL-22) and IL-17A are both effector cytokines produced by the T
H
17 lineage, and both were crucial for maintaining local control of the G...
Alternative Titles
Full title
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2901867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2901867
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1710
