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Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell...

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2910266

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

About this item

Full title

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2010-07, Vol.29 (14), p.2446-2460

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Non‐cell‐autonomous effect of mutant proteins expressed in glia has been implicated in several neurodegenerative disorders, whereas molecules mediating the toxicity are currently not known. We identified a novel molecule named
m
ultiple α‐heli
x
protein located at
ER
(Maxer) downregulated by mutant ataxin‐1 (Atx1) in Bergmann glia...

Alternative Titles

Full title

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2910266

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2910266

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2010.116

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