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Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?

Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2911017

Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?

About this item

Full title

Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?

Publisher

Switzerland

Journal title

Cellular and molecular life sciences : CMLS, 2008-06, Vol.65 (12), p.1842-1853

Language

English

Formats

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

Galanin (GAL) and GAL receptors (GALRs) are overexpressed in degenerating brain regions associated with cognitive decline in Alzheimer's disease (AD). The functional consequences of GAL plasticity in AD are unclear. GAL inhibits cholinergic transmission in the hippocampus and impairs spatial memory in rodent models, suggesting GAL overexpression ex...

Alternative Titles

Full title

Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2911017

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2911017

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-008-8159-2

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