Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation...
Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy
About this item
Full title
Author / Creator
Ojima, Koichi , Kawabata, Yukiko , Nakao, Harumi , Nakao, Kazuki , Doi, Naoko , Kitamura, Fujiko , Ono, Yasuko , Hata, Shoji , Suzuki, Hidenori , Kawahara, Hiroyuki , Bogomolovas, Julius , Witt, Christian , Ottenheijm, Coen , Labeit, Siegfried , Granzier, Henk , Toyama-Sorimachi, Noriko , Sorimachi, Michiko , Suzuki, Koichi , Maeda, Tatsuya , Abe, Keiko , Aiba, Atsu and Sorimachi, Hiroyuki
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Limb-girdle muscular dystrophy type 2A (LGMD2A) is a genetic disease that is caused by mutations in the calpain 3 gene (CAPN3), which encodes the skeletal muscle-specific calpain, calpain 3 (also known as p94). However, the precise mechanism by which p94 functions in the pathogenesis of this disease remains unclear. Here, using p94 knockin mice (te...
Alternative Titles
Full title
Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy
Authors, Artists and Contributors
Author / Creator
Kawabata, Yukiko
Nakao, Harumi
Nakao, Kazuki
Doi, Naoko
Kitamura, Fujiko
Ono, Yasuko
Hata, Shoji
Suzuki, Hidenori
Kawahara, Hiroyuki
Bogomolovas, Julius
Witt, Christian
Ottenheijm, Coen
Labeit, Siegfried
Granzier, Henk
Toyama-Sorimachi, Noriko
Sorimachi, Michiko
Suzuki, Koichi
Maeda, Tatsuya
Abe, Keiko
Aiba, Atsu
Sorimachi, Hiroyuki
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2912184
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2912184
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI40658
