Oxidation of multiple methionine residues impairs rapid sodium channel inactivation
Oxidation of multiple methionine residues impairs rapid sodium channel inactivation
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
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More information
Scope and Contents
Contents
Reactive oxygen species (ROS) readily oxidize the sulfur-containing amino acids cysteine and methionine (Met). The impact of Met oxidation on the fast inactivation of the skeletal muscle sodium channel Na
V
1.4 expressed in mammalian cells was studied by applying the Met-preferring oxidant chloramine-T or by irradiating the ROS-producing dye...
Alternative Titles
Full title
Oxidation of multiple methionine residues impairs rapid sodium channel inactivation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2913308
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2913308
Other Identifiers
ISSN
0031-6768
E-ISSN
1432-2013
DOI
10.1007/s00424-008-0477-6
