Effect of β2 -adrenergic receptor polymorphism on response to longacting β2 agonist in asthma (LARGE...
Effect of β2 -adrenergic receptor polymorphism on response to longacting β2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial
About this item
Full title
Author / Creator
Wechsler, Michael E, Dr , Kunselman, Susan J, MA , Chinchilli, Vernon M, Prof , Bleecker, Eugene, Prof , Boushey, Homer A, Prof , Calhoun, William J, Prof , Ameredes, Bill T, PhD , Castro, Mario, MD , Craig, Timothy J, Prof , Denlinger, Loren, MD , Fahy, John V, Prof , Jarjour, Nizar, Prof , Kazani, Shamsah, MD , Kim, Sophia, MD , Kraft, Monica, Prof , Lazarus, Stephen C, Prof , Lemanske, Robert F, Prof , Markezich, Amy, MD , Martin, Richard J, Prof , Permaul, Perdita, MD , Peters, Stephen P, Prof , Ramsdell, Joe, Prof , Sorkness, Christine A, Prof , Sutherland, E Rand, MD , Szefler, Stanley J, Prof , Walter, Michael J, MD , Wasserman, Stephen I, Prof and Israel, Elliot, MD
Publisher
Kidlington: Elsevier
Journal title
Language
English
Formats
Publication information
Publisher
Kidlington: Elsevier
Subjects
More information
Scope and Contents
Contents
Summary Background Some studies suggest that patients with asthma who are homozygous for arginine at the 16th aminoacid position of the β2 -adrenergic receptor (B16 Arg/Arg) benefit less from treatment with longacting β2 agonists and inhaled corticosteroids than do those homozygous for glycine (B16 Gly/Gly). We investigated whether there is a genot...
Alternative Titles
Full title
Effect of β2 -adrenergic receptor polymorphism on response to longacting β2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial
Authors, Artists and Contributors
Author / Creator
Kunselman, Susan J, MA
Chinchilli, Vernon M, Prof
Bleecker, Eugene, Prof
Boushey, Homer A, Prof
Calhoun, William J, Prof
Ameredes, Bill T, PhD
Castro, Mario, MD
Craig, Timothy J, Prof
Denlinger, Loren, MD
Fahy, John V, Prof
Jarjour, Nizar, Prof
Kazani, Shamsah, MD
Kim, Sophia, MD
Kraft, Monica, Prof
Lazarus, Stephen C, Prof
Lemanske, Robert F, Prof
Markezich, Amy, MD
Martin, Richard J, Prof
Permaul, Perdita, MD
Peters, Stephen P, Prof
Ramsdell, Joe, Prof
Sorkness, Christine A, Prof
Sutherland, E Rand, MD
Szefler, Stanley J, Prof
Walter, Michael J, MD
Wasserman, Stephen I, Prof
Israel, Elliot, MD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2914569
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2914569
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(09)61492-6
