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Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics

Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2929644

Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics

About this item

Full title

Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2009-09, Vol.325 (5946), p.1380-1384

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Bacterial nitric oxide synthases (bNOS) are present in many Gram-positive species and have been demonstrated to synthesize NO from arginine in vitro and in vivo. However, the physiological role of bNOS remains largely unknown. We show that NO generated by bNOS increases the resistance of bacteria to a broad spectrum of antibiotics, enabling the bac...

Alternative Titles

Full title

Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2929644

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2929644

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1175439

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