Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics
Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics
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Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Bacterial nitric oxide synthases (bNOS) are present in many Gram-positive species and have been demonstrated to synthesize NO from arginine in vitro and in vivo. However, the physiological role of bNOS remains largely unknown. We show that NO generated by bNOS increases the resistance of bacteria to a broad spectrum of antibiotics, enabling the bac...
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Full title
Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2929644
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2929644
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1175439