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Rb regulates fate choice and lineage commitment in vivo

Rb regulates fate choice and lineage commitment in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2933655

Rb regulates fate choice and lineage commitment in vivo

About this item

Full title

Rb regulates fate choice and lineage commitment in vivo

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2010-08, Vol.466 (7310), p.1110-1114

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Rb suppressor and cell fate
The tumour suppressor Rb (retinoblastoma protein) is mutated in about one-third of human tumours. It suppresses the activity of certain transcription factors and potentiates the activity of others, and has been shown to affect the differentiation of different cell lineages
in vitro
. Jacqueline Lees and colleagu...

Alternative Titles

Full title

Rb regulates fate choice and lineage commitment in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2933655

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2933655

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature09264

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