Cytotoxicity Associated with Artemis Overexpression After Lentiviral Vector-Mediated Gene Transfer
Cytotoxicity Associated with Artemis Overexpression After Lentiviral Vector-Mediated Gene Transfer
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Author / Creator
Publisher
Larchmont, NY: Liebert
Journal title
Language
English
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Publisher
Larchmont, NY: Liebert
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Scope and Contents
Contents
Artemis is a hairpin-opening endonuclease involved in nonhomologous end-joining and V(D)J recombination. Deficiency of Artemis results in radiation-sensitive severe combined immunodeficiency (SCID) characterized by complete absence of T and B cells due to an arrest at the receptor recombination stage. We have generated several lentiviral vectors fo...
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Full title
Cytotoxicity Associated with Artemis Overexpression After Lentiviral Vector-Mediated Gene Transfer
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2938362
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2938362
Other Identifiers
ISSN
1043-0342
E-ISSN
1557-7422
DOI
10.1089/hum.2009.162