Variation in Transcription Factor Binding among Humans
Variation in Transcription Factor Binding among Humans
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Author / Creator
Kasowski, Maya , Grubert, Fabian , Heffelfinger, Christopher , Hariharan, Manoj , Asabere, Akwasi , Waszak, Sebastian M. , Habegger, Lukas , Rozowsky, Joel , Shi, Minyi , Urban, Alexander E. , Hong, Mi-Young , Karczewski, Konrad J. , Huber, Wolfgang , Weissman, Sherman M. , Gerstein, Mark B. , Korbel, Jan O. and Snyder, Michael
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Differences in gene expression may play a major role in speciation and phenotypic diversity. We examined genome-wide differences in transcription factor (TF) binding in several humans and a single chimpanzee by using chromatin immunoprecipitation followed by sequencing. The binding sites of RNA polymerase II (Polli) and a key regulator of immune re...
Alternative Titles
Full title
Variation in Transcription Factor Binding among Humans
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2938768
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2938768
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1183621
