Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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A cofactor for the E3 ubiquitin ligase TRAF2
TRAF2 (tumour-necrosis factor receptor-associated factor 2), a component of the NF-κB activation pathway important in inflammatory, anti-apoptotic, and immune processes, is shown to be a target of sphingosine kinase 1, one of the isoenzymes that generates the pro-survival lipid mediator sphingosine-1-...
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Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2946785
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2946785
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09128
